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- サプライヤー
- TargteMol
- カタログNo.
- TMPY-00834
- 製品名称
- IGF1R/CD221 Protein, Human, Recombinant (His)
- タンパク質名
- IGF1R/CD221
- Species
- Human
- HOST
- HEK293 Cells
- 100μg: -
- お問い合わせ
Overview
| Synonyms | IGF-I R, IGFR, IGFIR, IGF1 Receptor, JTK13, insulin-like growth factor 1 receptor, CD221 |
|---|---|
| Characteristics | 1. Immobilized Anti-IGF-1R Antibody at 2 μg/mL (100 μL/well) can bind Recombinant Human IGF1R / CD221 Protein (His Tag) , the EC50 is 1.2-3.6 ng/mL(QC tested). 2.Captured IGF1R on?NTA Chip can bind IGF1 with an affinity constant of 0.1317 ?M as determined in a SPR assay (Routinely tested). 3.Loaded Anti-IGF-1R Antibody, human IgG1 on ProA Biosensor, can bind Recombinant Human IGF1R Protein, His Tag with an affinity constant of 0.808nM as determined in BLI assay (Routinely tested). |
| Endotoxin Level | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Purity | 98.20% |
| Description | IGF1R/CD221 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 81 kDa and the accession number is P08069. |
| Reference | Bhr C, et al. (2004) The insulin like growth factor-1 receptor (IGF-1R) as a drug target: novel approaches to cancer therapy. Growth Horm IGF Res. 14 (4): 287-95.,Front Biosci. 14: 352-75.Annenkov A. (2009) The insulin-like growth factor (IGF) receptor type 1 (IGF1R) as an essential component of the signalling network regulating neurogenesis. Mol Neurobiol. 40 (3): 195-215.,Gualco E, et al. (2009) IGF-IR in neuroprotection and brain tumors.,Riedemann J, et al. (2006) IGF1R signalling and its inhibition. Endocr Relat Cancer. 13 Suppl 1: 33-43. |
| URL | https://www.targetmol.com/recombinant-protein/igf1r_protein_human_recombinant_ecd_his_tag_ |
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