タンパク質、抗体、アッセイキット
タンパク質カタログ
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- サプライヤー
- TargteMol
- カタログNo.
- TMPY-00779
- 製品名称
- DPP4/CD26 Protein, Human, Recombinant
- タンパク質名
- DPP4/CD26
- Species
- Human
- HOST
- HEK293 Cells
- 50μg: -
- お問い合わせ
Overview
Synonyms | TP103, CD26, ADCP2, DPPIV, ADABP, dipeptidylpeptidase 4 |
---|---|
Characteristics | 1. Measured by its ability to cleave the fluorogenic peptide substrate, Gly-Pro-7-amido-4-methylcoumarin (GP-AMC). The specific activity is > 2,500 pmoles/min/μg. 2. Using the Octet RED System, the affinity constant (Kd) of human DPP4 bound to Spike (HCoV-EMC/2012) was 20 nM. 3. Using the Octet RED System, the affinity constant (Kd) of human DPP4 bound to Spike (HCoV-EMC/2012) was 50 nM. 4. Using the Octet RED System, the affinity constant (Kd) of human DPP4 bound to Spike (HCoV-EMC/2012) (ECD, aa 1-1297) was 33 nM. 5. Using the Octet RED System, the affinity constant (Kd) of human DPP4 bound to Spike-His (aa 1-760) was 12 nM. |
Endotoxin Level | < 1.0 EU/μg of the protein as determined by the LAL method. |
Purity | SDS-PAGE: 97%; SEC-HPLC: 99.3% |
Description | DPP4/CD26 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 85.4 kDa and the accession number is P27487. |
Reference | Matteucci E, et al. (2009) Dipeptidyl peptidase-4 (CD26): knowing the function before inhibiting the enzyme. Curr Med Chem. 16(23): 2943-51.,HAvre PA, et al. (2008) The role of CD26/dipeptidyl peptidase IV in cancer. Front Biosci. 13: 1634-45.,De Chiara L, et al. (2009) Soluble CD26 levels and its association to epidemiologic parameters in a sample population. Dis Markers. 7(6): 311-6.,Doupis J, et al. (2008) DPP4 inhibitors: a new approach in diabetes treatment. Adv Ther. 25(7): 627-43. |
URL | https://www.targetmol.com/recombinant-protein/dpp4_cd26_protein_human_recombinant_hplc_verified |