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サプライヤー
TargteMol
カタログNo.
TMPY-00779
製品名称
DPP4/CD26 Protein, Human, Recombinant
タンパク質名
DPP4/CD26
Species
Human
HOST
HEK293 Cells
50μg: -
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Overview

Synonyms TP103, CD26, ADCP2, DPPIV, ADABP, dipeptidylpeptidase 4
Characteristics 1. Measured by its ability to cleave the fluorogenic peptide substrate, Gly-Pro-7-amido-4-methylcoumarin (GP-AMC). The specific activity is > 2,500 pmoles/min/μg.
2. Using the Octet RED System, the affinity constant (Kd) of human DPP4 bound to Spike (HCoV-EMC/2012) was 20 nM.
3. Using the Octet RED System, the affinity constant (Kd) of human DPP4 bound to Spike (HCoV-EMC/2012) was 50 nM.
4. Using the Octet RED System, the affinity constant (Kd) of human DPP4 bound to Spike (HCoV-EMC/2012) (ECD, aa 1-1297) was 33 nM.
5. Using the Octet RED System, the affinity constant (Kd) of human DPP4 bound to Spike-His (aa 1-760) was 12 nM.
Endotoxin Level < 1.0 EU/μg of the protein as determined by the LAL method.
Purity SDS-PAGE: 97%; SEC-HPLC: 99.3%
Description DPP4/CD26 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 85.4 kDa and the accession number is P27487.
Reference Matteucci E, et al. (2009) Dipeptidyl peptidase-4 (CD26): knowing the function before inhibiting the enzyme. Curr Med Chem. 16(23): 2943-51.,HAvre PA, et al. (2008) The role of CD26/dipeptidyl peptidase IV in cancer. Front Biosci. 13: 1634-45.,De Chiara L, et al. (2009) Soluble CD26 levels and its association to epidemiologic parameters in a sample population. Dis Markers. 7(6): 311-6.,Doupis J, et al. (2008) DPP4 inhibitors: a new approach in diabetes treatment. Adv Ther. 25(7): 627-43.
URL https://www.targetmol.com/recombinant-protein/dpp4_cd26_protein_human_recombinant_hplc_verified

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