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サプライヤー
TargteMol
カタログNo.
TMPY-00778
製品名称
DPP4/CD26 Protein, Human, Recombinant (hFc)
タンパク質名
DPP4/CD26
Species
Human
HOST
HEK293 Cells
50μg: -
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Overview

Synonyms DPPIV, TP103, ADABP, CD26, ADCP2, dipeptidylpeptidase 4
Characteristics 1. Measured by its ability to bind recombinant Cynomolgus CXCL12 in a functional ELISA.
2. Measured by its ability to bind recombinant Human SDF1b in a functional ELISA.
3. Loaded Fc-DPPIV on ProA Biosensor, can bind MERS-CoV Spike/RBD Protein fragment (RBD, aa 367-606, His Tag) with an affinity constant of 1.04 nM as determined by Octet RED System.
4. Loaded Fc-DPPIV on ProA Biosensor, can bind MERS-CoV Spike/S1 Protein (S1 Subunit, aa 1-725, His Tag) with an affinity constant of 0.02 nM as determined by Octet RED System.
5. Loaded Fc-DPPIV on ProA Biosensor, can bind MERS-CoV Spike/RBD Protein fragment (RBD, aa 367-606, His Tag) with an affinity constant of 1.04 nM as determined by Octet RED System.
6. Loaded Fc-DPPIV on ProA Biosensor, can bind MERS-CoV Spike/S1 Protein (S1 Subunit, aa 1-725, His Tag) with an affinity constant of 0.02 nM as determined by Octet RED System.
Endotoxin Level < 1.0 EU/μg of the protein as determined by the LAL method.
Purity 92.90%
Description DPP4/CD26 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 112 kDa and the accession number is P27487.
Reference Doupis J, et al. (2008) DPP4 inhibitors: a new approach in diabetes treatment. Adv Ther. 25(7): 627-43.,HAvre PA, et al. (2008) The role of CD26/dipeptidyl peptidase IV in cancer. Front Biosci. 13: 1634-45.,Matteucci E, et al. (2009) Dipeptidyl peptidase-4 (CD26): knowing the function before inhibiting the enzyme. Curr Med Chem. 16(23): 2943-51.,De Chiara L, et al. (2009) Soluble CD26 levels and its association to epidemiologic parameters in a sample population. Dis Markers. 7(6): 311-6.
URL https://www.targetmol.com/recombinant-protein/dpp4_cd26_protein_human_recombinant_hfc_tag_hplc_verified

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