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- サプライヤー
- TargteMol
- カタログNo.
- TMPY-00699
- 製品名称
- CD155/PVR Protein, Human, Recombinant (hFc)
- タンパク質名
- CD155/PVR
- Species
- Human
- HOST
- HEK293 Cells
- 100μg: -
- お問い合わせ
Overview
| Synonyms | poliovirus receptor, NECL5, HVED, PVS, Necl-5, TAGE4, CD155 |
|---|---|
| Characteristics | Immobilized Recombinant Human TIGIT / VSTM3 Protein (His Tag) at 2 μg/mL (100 μl/well) can bind Recombinant Human CD155/PVR/NECL5 Protein (Fc Tag) , the EC50 is 10-30 ng/mL. |
| Endotoxin Level | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Purity | SDS-PAGE: 97.7%; SEC-HPLC: 98.4% |
| Description | CD155/PVR Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.8 kDa and the accession number is P15151-1. |
| Reference | Freistadt MS, et al. (2000) Hematopoietic cells from CD155-transgenic mice express CD155 and support poliovirus replication ex vivo. Microb Pathog. 29(4): 203-12.,Sato T, et al. (2005) Common signaling pathway is used by the trans-interaction of Necl-5/Tage4/PVR/CD155 and nectin, and of nectin and nectin during the formation of cell-cell adhesion. Cancer Sci. 96(9): 578-89.,Kakunaga S, et al. (2004) Enhancement of serum- and platelet-derived growth factor-induced cell proliferation by Necl-5/Tage4/poliovirus receptor/CD155 through the Ras-Raf-MEK-ERK signaling. J Biol Chem. 279(35): 36419-25.,Minami Y, et al. (2007) Involvement of up-regulated Necl-5/Tage4/PVR/CD155 in the loss of contact inhibition in transformed NIH3T3 cells. Biochem Biophys Res Commun. 352(4): 856-60.,Sato T, et al. (2004) Involvement of heterophilic trans-interaction of Necl-5/Tage4/PVR/CD155 with nectin-3 in formation of nectin- and cadherin-based adherens junctions. Genes Cells. 9(9): 791-9. |
| URL | https://www.targetmol.com/recombinant-protein/cd155_pvr_protein_human_recombinant_ecd_hfc_tag_ |
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