I-309/CCL1 Protein, Human, Recombinant (hFc) [TMPY-00695]

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Synonyms	chemokine (C-C motif) ligand 1, TCA3, SISe, I-309, SCYA1, P500
Characteristics	Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Endotoxin Level	< 1.0 EU/μg of the protein as determined by the LAL method.
Purity	94.80%
Description	I-309 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 35 kDa and the accession number is P22362.
Reference	Boneberg EM,et al.(2009) Soluble CD146 is generated by ectodomain shedding of membrane CD146 in a calcium-induced, matrix metalloprotease-dependent process. Microvasc Res. 78(3): 325-31.,Taira E,et al.(2004) Characterization of Gicerin/MUC18/CD146 in the rat nervous system. J Cell Physiol. 198(3): 377-87.,Fritzsche FR,et al.(2008) CD146 protein in prostate cancer: revisited with two different antibodies. Pathology. 40(5): 457-64.,Bidlingmaier S,et al.(2009) Identification of MCAM/CD146 as the target antigen of a human monoclonal antibody that recognizes both epithelioid and sarcomatoid types of mesothelioma. Cancer Res. 69(4): 1570-7.,Mills L,et al.(2002) Fully human antibodies to MCAM/MUC18 inhibit tumor growth and metastasis of human melanoma. Cancer Res. 62(17): 5106-14.
URL	https://www.targetmol.com/recombinant-protein/i_309_protein_human_recombinant_hfc_tag_

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