Alkaline Phosphatase/ALPL Protein, Human, Recombinant (His) [TMPY-00663]

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Synonyms	alkaline phosphatase, liver/bone/kidney, TNSALP, AP-TNAP, HOPS, TNAP, APTNAP
Characteristics	Measured by its ability to cleave a fluorogenic substrate, 4-Methylumbelliferyl phosphate (4-MUP). The specific activity is > 50, 000 pmoles/min/μg.
Endotoxin Level	< 1.0 EU/μg of the protein as determined by the LAL method.
Purity	SDS-PAGE: 95.3%; SEC-HPLC: 96.9%
Description	Alkaline Phosphatase/ALPL Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 55 kDa and the accession number is A0A024RAB4.
Reference	Brun-Heath I, et al. (2011) Differential expression of the bone and the liver tissue non-specific alkaline phosphatase isoforms in brain tissues. Cell Tissue Res. 343(3): 521-36.,Whyte MP, et al. (1995) Alkaline phosphatase: placental and tissue-non-specific isoenzymes hydrolyze phosphoethanolamine, inorganic pyrophosphate, and pyridoxal 5-phosphate. J Clin Invest. 95: 1440-5.,Whyte MP. (1994) Hypophosphatasia and the role of alkaline phosphatase in skeletal mineralization. Endocrinol Rev. 4: 439-61.,Weinreb M, et al. (1990) Different pattern of alkaline phosphatase, osteopontin and osteocalcin expression in developing rat bone visualized by in situ hybridization. J Bone Miner Res. 5: 831-42.
URL	https://www.targetmol.com/recombinant-protein/alkaline_phosphatase_alpl_protein_human_recombinant_his_tag_hplc_verified

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