ITGB1 Protein, Human, Recombinant (His) [TMPY-00476]

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Synonyms	VLAB, integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12), integrin, β1 (fibronectin receptor, βpolypeptide, antigen CD29 includes MDF2, MSK12), GPIIA, MSK12, CD29, Integrin β1, FNRB, MDF2, VLA-β, VLA-BETA
Characteristics	Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Endotoxin Level	< 1.0 EU/μg of the protein as determined by the LAL method.
Purity	92.40%
Description	ITGB1 (Integrin Subunit Beta 1) is a Protein Coding gene. This gene encodes a beta subunit, which is a type 1 transmembrane protein of the integrin beta chain family. ITGB1 is a heterodimeric cell-surface receptor involved in cell functions such as proliferation, migration, invasion, and survival. ITGB1 has been recognized to play a major role in tumor growth, invasion, and metastasis. Using luciferase assays, the researcher identified ITGB1 as a direct target of miR-134. ITGB1 is a direct target of miR-493-5p suggesting that ITGB1 and miR-493-5p may have potential prognostic value and may be useful as tumor biomarkers for the diagnosis of NSCLC patients. Diseases associated with ITGB1 include Gallbladder Cancer and Breast Cancer.
Reference	-
URL	https://www.targetmol.com/recombinant-protein/integrin_beta_1_protein_human_recombinant_ecd_his_tag_

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