FGFR2 Protein, Human, Recombinant (alpha IIIb, hFc) [TMPY-00423]

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Synonyms	BFR-1, KGFR, TK25, JWS, FGFR2 α(IIIb), CD332, fibroblast growth factor receptor 2, ECT1, K-SAM, BEK, CFD1, TK14, BBDS, CEK3
Characteristics	1. Measured by its ability to inhibit FGF-acidic dependent proliferation of Balb/c 3T3 mouse fibroblasts.?The ED50 for this effect is typically 0.5-4 ng/mL. 2. Measured by its ability to bind recombinant Fc-FGF10 in a functional ELISA.
Endotoxin Level	< 1.0 EU/μg of the protein as determined by the LAL method.
Purity	96.80%
Description	FGFR2 Protein, Human, Recombinant (alpha IIIb, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 66.3 kDa and the accession number is P21802-17.
Reference	Marie PJ,et al.(2003) Regulation of human cranial osteoblast phenotype by FGF-2, FGFR-2 and BMP-2 signaling. Histol. 17(3):877-85.,Orr-Urtreger A,et al.(1993) Developmental localization of the splicing alternatives of fibroblast growth factor receptor-2 (FGFR2). Dev Biol. 158(2):475-86.,Park WJ,et al.(1996) Novel FGFR2 mutations in Crouzon and Jackson-Weiss syndromes show allelic heterogeneity and phenotypic variability. Hum Mol Genet. 4(7):1229-33.
URL	https://www.targetmol.com/recombinant-protein/fgfr2_protein_human_recombinant_alpha_iiib_hfc_tag_hplc_verified

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