Insulin Protein, Human, Recombinant [TMPY-00395]

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Synonyms	IDDM1, MODY10, ILPR, IDDM2, IRDN, IDDM, insulin, INS
Characteristics	Measured in a serum-free cell proliferation assay using MCF?7 human breast cancer cells. The ED50 for this effect is typically 0.2-1 ?g/mL.
Endotoxin Level	Please contact us for more information.
Purity	97.20%
Description	INS (Insulin) is a Protein Coding gene. This gene encodes insulin, a peptide hormone that plays a vital role in the regulation of carbohydrate and lipid metabolism. After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. The binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. Diseases associated with INS include Hyperproinsulinemia and Maturity-Onset Diabetes Of The Young, Type 10. A multitude of mutant alleles with phenotypic effects has been identified, including insulin-dependent diabetes mellitus, permanent neonatal diabetes mellitus, maturity-onset diabetes of the young type 10, and hyperproinsulinemia.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
Reference	Veedfald S, Plamboeck A, Deacon C F,et al.Cephalic phase secretion of insulin and other enteropancreatic hormones in humans[J]. American Journal of Physiology-Gastrointestinal and Liver Physiology, 2016, 310(1): G43-G51.
URL	https://www.targetmol.com/recombinant-protein/insulin_protein_human_recombinant

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