FGFR3 Protein, Human, Recombinant (alpha IIIb, His) [TMPY-00341]

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Synonyms	CEK2, HSFGFR3EX, fibroblast growth factor receptor 3, JTK4, FGFR3 α(IIIb), CD333, ACH
Characteristics	Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Endotoxin Level	< 1.0 EU/μg of the protein as determined by the LAL method.
Purity	SDS-PAGE: 96.1%; SEC-HPLC: 99.6%
Description	FGFR3 Protein, Human, Recombinant (alpha IIIb, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P22607-2.
Reference	Keegan K,et al.(1991) Isolation of an additional member of the fibroblast growth factor receptor family, FGFR-3. Proc Natl Acad Sci. 88(4):1095-9.,Schweitzer DN,et al.(2001) Subtle radiographic findings of achondroplasia in patients with Crouzon syndrome with acanthosis nigricans due to an Ala391Glu substitution in FGFR3. Am J Med Genet. 98 (1):75-91.,Lamy A,et al.(2006) Molecular profiling of bladder tumors based on the detection of FGFR3 and TP53 mutations. J Urol. 176(6 Pt 1):2686-9.,HAfner C,et al.(2007) FGFR3 mutations in epidermal nevi and seborrheic keratoses: lessons from urothelium and skin. J Invest Dermatol. 127(7):1572-3.
URL	https://www.targetmol.com/recombinant-protein/fgfr3_protein_human_recombinant_ecd_alpha_iiib_his_tag_

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