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- サプライヤー
- TargteMol
- カタログNo.
- TMPY-00033
- 製品名称
- 4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (hFc)
- タンパク質名
- 4-1BB Ligand/TNFSF9
- Species
- Human
- HOST
- HEK293 Cells
- 100μg: -
- お問い合わせ
Overview
| Synonyms | 4-1BB-L, tumor necrosis factor (ligand) superfamily, member 9, 4-1BBL, CD137L |
|---|---|
| Characteristics | 1. Immobilized human TNFRSF9 at 10μg/mL (100μL/well) can bind human TNFSF9 , the EC50 of human TNFSF9 is 7-40ng/mL. 2. Measured by its ability to induce IL-8 secretion by HT1080 transfected with human CD137. The EC50 for this effect is typically 0.3-1.2 μg/mL. |
| Endotoxin Level | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Purity | 88.90% |
| Description | 4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 47.9 kDa and the accession number is A0A0U5J8I0. |
| Reference | Wang C, et al. (2009) Immune regulation by 4-1BB and 4-1BBL: complexities and challenges. Immunol Rev. 229(1): 192-215.,HAbib-Agahi M, et al. (2009) 4-1BBL costimulation retrieves CD28 expression in activated T cells. Cell Immunol. 256(1-2): 39-46.,Cheung CT, (2007) Neutralizing anti-4-1BBL treatment improves cardiac function in viral myocarditis. Lab Invest. 87(7): 651-61. |
| URL | https://www.targetmol.com/recombinant-protein/4_1bb_ligand_tnfsf9_protein_human_recombinant_ecd_hfc_tag_ |
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