DLL3 Protein, Human, Recombinant (His & Avi), Biotinylated [TMPK-01207]

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Synonyms	Pudgy, δ3, SCDO1δ3, Delta3, SCDO1delta3, SCDO1, DLL3
Characteristics	Immobilized Biotinylated Human DLL3 Domain (311-479) ,His Tag at 0.5μg/ml (100μl/well) on the streptavidin precoated plate (5μg/ml). Dose response curve for Anti-DLL3 Antibody, hFc Tag with the EC50 of 1.6ng/ml determined by ELISA.
Endotoxin Level	< 1 EU/μg by the LAL method.
Purity	> 95%
Description	Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity). DLL3 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 21.20 kDa and the accession number is Q9NYJ7-1.
Reference	Saunders L R, et al. A DLL3-targeted antibody-drug conjugate eradicates high-grade pulmonary neuroendocrine tumor-initiating cells in vivo[J]. Science Translational Medicine, 2015.
URL	https://www.targetmol.com/recombinant-protein/dll3_domain_311_479_protein_human_recombinant_his_avi_biotinylated

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