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- サプライヤー
- TargteMol
- カタログNo.
- TMPK-01158
- 製品名称
- Kallikrein 5/KLK5 Protein, Mouse, Recombinant (His)
- タンパク質名
- Kallikrein 5/KLK5
- Species
- Mouse
- HOST
- HEK293 Cells
- 100μg: -
- お問い合わせ
Overview
| Synonyms | SCTE, KLKL2, KLK5, KLK-L2, Klnc, Kallikrein c |
|---|---|
| Characteristics | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Endotoxin Level | < 1 EU/μg by the LAL method. |
| Purity | > 95% |
| Description | The inhibition of kallikrein 5 (KLK5) has been identified as a potential strategy for treatment of the genetic skin disorder Netherton syndrome, in which loss-of-function mutations in the SPINK5 gene lead to down-regulation of the endogenous inhibitor LEKTI-1 and profound skin-barrier defects with severe allergic manifestations. To aid in the development of a medicine for this target, an X-ray crystallographic system was developed to facilitate fragment-guided chemistry and knowledge-based drug-discovery approaches. |
| Reference | 4809 |
| URL | https://www.targetmol.com/recombinant-protein/kallikrein_5_klk5_protein_mouse_recombinant_his_ |
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