タンパク質、抗体、アッセイキット
タンパク質カタログ
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- サプライヤー
- TargteMol
- カタログNo.
- TMPK-00830
- 製品名称
- P-Selectin Protein, Human, Recombinant (Avi & His), Biotinylated
- タンパク質名
- P-Selectin
- Species
- Human
- HOST
- HEK293 Cells
- 100μg: -
- お問い合わせ
Overview
Synonyms | FLJ45155, CD62P, GRMP, CD62, P-Selectin, PSEL, GMP140, LECAM3, SELP, PADGEM |
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Characteristics | Immobilized Biotinylated Human P-Selectin, His Tag at 1μg/ml (100μl/Well) on streptavidin (5μg/ml) precoated plate. Dose response curve for Anti-P-Selectin Antibody, hFc Tag with the EC50 of 2.9ng/ml determined by ELISA. |
Endotoxin Level | < 1 EU/μg by the LAL method. |
Purity | > 95% as determined by Bis-Tris PAGE > 95% as determined by HPLC |
Description | Human P-Selectin (GMP-140, LECAM-3, PADGEM, CD62P), a member of the Selectin family, is a cell surface glycoprotein expressed by activated platelets and endothelial cells. A SLe(x)-type proteoglycan, which through high affinity, calcium-dependent interactions with E-, P- and L-selectins, mediates rapid rolling of leukocytes over vascular surfaces during the initial steps in inflammation. |
Reference | Ataga K I, et al. Crizanlizumab for the Prevention of Pain Crises in Sickle Cell Disease[J]. New England Journal of Medicine, 2016, 376(5):429-439. |
URL | https://www.targetmol.com/recombinant-protein/p_selectin_cd62p_protein_human_recombinant_his_avi_biotinylated |