タンパク質、抗体、アッセイキット
タンパク質カタログ
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- サプライヤー
- TargteMol
- カタログNo.
- TMPK-00782
- 製品名称
- PLAU/uPA Protein, Mouse, Recombinant (His & Avi)
- タンパク質名
- PLAU/uPA
- Species
- Mouse
- HOST
- HEK293 Cells
- 100μg: -
- お問い合わせ
Overview
Synonyms | PLAU, UPA, BDPLT5, ATF, u-PA, QPD, Urokinase, URK |
---|---|
Characteristics | Human uPAR, hFc Tag captured on CM5 Chip via Protein A can bind Mouse PLAU, His Tag with an affinity constant of 9.98 μM as determined in SPR assay. |
Endotoxin Level | < 1 EU/μg by the LAL method. |
Purity | > 95% |
Description | Plasminogen activator, urokinase (uPA) is a secreted serine protease whose Dysregulation is often accompanied by various cancers. PLAU inhibition could suppress tumor growth. Collectively, PLAU is necessary for tumor progression and can be a diagnostic and prognostic biomarker in HNSCC. PLAU/uPA Protein, Mouse, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 49.00 kDa and the accession number is P06869. |
Reference | Chen G, et al. PLAU Promotes Cell Proliferation and Epithelial-Mesenchymal Transition in Head and Neck Squamous Cell Carcinoma. Front Genet. 2021 May 20;12:651882. doi: 10.3389/fgene.2021.651882. PMID: 34093649; PMCID: PMC8173099. |
URL | https://www.targetmol.com/recombinant-protein/plau_upa_protein_mouse_recombinant_his_avi_ |