PRNP/Prion Protein, Mouse, Recombinant (hFc) [TMPK-00775]

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Synonyms	Major prion protein, PrP, ALTPRP, PRIP, PRNP
Characteristics	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Endotoxin Level	< 1 EU/μg by the LAL method.
Purity	> 95% as determined by Bis-Tris PAGE
Description	Prion protein gene (PRNP) variants determine the susceptibility of humans, sheep and mice to prion diseases, whereas polymorphisms in the open reading frame (ORF) of bovine PRNP seem to be unrelated to the incidence of bovine spongiform encephalopathy (BSE). According to the latest reports, the genetic susceptibility of cattle to BSE is associated with polymorphisms ofthe regulatory region of the PRNP gene and the level ofits expression.
Reference	Gurgul A, S?ota E. Effect of bovine PRNP gene polymorphisms on BSE susceptibility in cattle. Folia Biol (Krakow). 2007;55(3-4):81-6. doi: 10.3409/173491607781492533. PMID: 18274249.
URL	https://www.targetmol.com/recombinant-protein/prnp_protein_mouse_recombinant_hfc_

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