タンパク質、抗体、アッセイキット
タンパク質カタログ
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- サプライヤー
- TargteMol
- カタログNo.
- TMPK-00618
- 製品名称
- FcRH5/FcRL5 Protein, Human, Recombinant (His)
- タンパク質名
- FcRH5/FcRL5
- Species
- Human
- HOST
- HEK293 Cells
- 100μg: -
- お問い合わせ
Overview
Synonyms | FcR-like protein 5, CD307, BXMAS1, FcRH5, IFGP5, CD307e, FcRL5 |
---|---|
Characteristics | Immobilized Human FcRH5, His Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Anti-FcRH5 Antibody, hFc Tag with the EC50 of 21.1ng/ml determined by ELISA. |
Endotoxin Level | < 1 EU/μg by the LAL method. |
Purity | - |
Description | FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE), a potent anti-mitotic agent. FcRH5/FcRL5 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 92.38 kDa and the accession number is AAK93971. |
Reference | Elkins K, et al. FcRL5 as a target of antibody-drug conjugates for the treatment of multiple myeloma. Mol Cancer Ther. 2012;11(10):2222-2232. doi:10.1158/1535-7163.MCT-12-0087. |
URL | https://www.targetmol.com/recombinant-protein/fcrh5_fcrl5_protein_human_recombinant_his_ |