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タンパク質カタログ
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- サプライヤー
- TargteMol
- カタログNo.
- TMPK-00474
- 製品名称
- IL-22RA1 Protein, Cynomolgus, Recombinant (His)
- タンパク質名
- IL-22RA1
- Species
- Cynomolgus
- HOST
- HEK293 Cells
- 100μg: -
- お問い合わせ
Overview
| Synonyms | CRF2-9, IL22R1, IL-22R-α-1, IL-22RA1, zcytoR11, IL22R, IL-22R-alpha-1, IL-22R α1, IL-TIF-R1 |
|---|---|
| Characteristics | Cynomolgus IL-22R alpha 1, His Tag immobilized on CM5 Chip can bind Cynomolgus IL-22, His Tag with an affinity constant of 60.21 nM as determined in SPR assay. |
| Endotoxin Level | < 1 EU/μg by the LAL method. |
| Purity | > 95% |
| Description | IL-22 receptor, also known as IL-22 R alpha 1 and CRF2-9, is an approximately 65 kDa transmembrane glycoprotein in the type II cytokine receptor family (CRF).Component of the receptor for IL20, IL22 and IL24. Component of IL22 receptor formed by IL22RA1 and IL10RB enabling IL22 signaling via JAK/STAT pathways. IL22 also induces activation of MAPK1/MAPK3 and Akt kinases pathways. Component of one of the receptor for IL20 and IL24 formed by IL22RA1 and IL20RB also signaling through STATs activation. Mediates IL24 antiangiogenic activity as well as IL24 inhibitory effect on endothelial cell tube formation and differentiation. |
| Reference | Blake S J, Teng M W L. Role of IL-17 and IL-22 in autoimmunity and cancer[J]. Actas Dermo-Sifiliogr?ficas, 2014, 105S1(Suppl 1):41-50. |
| URL | https://www.targetmol.com/recombinant-protein/il_22r_alpha_1_protein_cynomolgus_recombinant_his_ |
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