SARS-COV-2 Spike S Trimer Protein (D614G, His & Avi) [TMPK-00435]

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Synonyms	S protein, Spike glycoprotein, COVID-19, S glycoprotein
Characteristics	Immobilized SARS-COV-2 Spike S Trimer (D614G) , His Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Human ACE2, hFc Tag with the EC50 of 10.6ng/ml determined by ELISA.
Endotoxin Level	< 1 EU/μg by the LAL method.
Purity	> 95% as determined by Bis-Tris PAGE > 95% as determined by HPLC
Description	The SARS-CoV-2 spike (S) protein variant D614G supplanted the ancestral virus worldwide, reaching near fixation in a matter of months. Recently, that D614G was been found more infectious than the ancestral form on human lung cells, colon cells, and on cells rendered permissive by ectopic expression of human ACE2 or of ACE2 orthologs from various mammals, including Chinese rufous horseshoe bat and Malayan pangolin.
Reference	Yurkovetskiy L, et al. Structural and Functional Analysis of the D614G SARS-CoV-2 Spike Protein Variant. Cell. 2020 Oct 29;183(3):739-75e8. doi: 10.1016/j.cell.2020.09.032. Epub 2020 Sep 15. PMID: 32991842; PMCID: PMC7492024.
URL	https://www.targetmol.com/recombinant-protein/spike_s_trimer_d614g_protein_sars_cov_2_recombinant_his_avi_

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