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- サプライヤー
- TargteMol
- カタログNo.
- TMPK-00383
- 製品名称
- ACE2/ACEH Protein, Human, Recombinant (His & Avi)
- タンパク質名
- ACE2/ACEH
- Species
- Human
- HOST
- HEK293 Cells
- 100μg: -
- お問い合わせ
Overview
| Synonyms | ACE2, ACE-2, ACEH |
|---|---|
| Characteristics | 1. Immobilized Human ACE2, His Tag at 5μg/ml (100μl/well) on the plate. Dose response curve for SARS-COV-2 Spike RBD, hFc Tag with the EC50 of 8.0ng/ml determined by ELISA. 2. SARS-COV-2 Spike S1, hFc Tag captured on CM5 Chip via Protein A can bind Human ACE2, His Tag with an affinity constant of 3.80 nM as determined in SPR assay. |
| Endotoxin Level | < 1 EU/μg by the LAL method. |
| Purity | > 95% |
| Description | ACE2 (Angiotensin I Converting Enzyme 2) is a Protein Coding gene. Diseases associated with ACE2 include Severe Acute Respiratory Syndrome and Neurogenic Hypertension.The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. ACE2/ACEH Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 86.5 kDa and the accession number is Q9BYF1-1. |
| Reference | Kuba K, et al. A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus?induced lung injury[J]. Nature Medicine, 2005, 11(8):875-879. |
| URL | https://www.targetmol.com/recombinant-protein/ace2_aceh_protein_human_recombinant_his_avi_ |
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