HGF Protein, Human, Recombinant (hFc) [TMPK-00369]

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Synonyms	HPTA, HGF, F-TCF, HGFB, SF, F-TCFB, DFNB39, Hepatopoietin-A
Characteristics	Immobilized Human HGF R, His Tag at 2μg/ml (100μl/Well) on the plate. Dose response curve for Human HGF, hFc Tag with the EC50 of 15.2ng/ml determined by ELISA.
Endotoxin Level	< 1 EU/μg by the LAL method.
Purity	> 95%
Description	Hepatocyte growth factor (HGF) is an important component of the pathophysiology of IR, with increased levels in most common IR conditions, including obesity. HGF has a role in the metabolic flux of glucose in different insulin sensitive cell types; plays a key role in β-cell homeostasis; and is capable of modulating the inflammatory response.HGF plays a central role in these metabolic disorders,HGF levels could be employed as a biomarker for disease status/progression, and HGF/c-Met signaling pathway modulators could effectively regulate IR and treat diabetes.
Reference	Oliveira AG, et al. The Role of Hepatocyte Growth Factor (HGF) in Insulin Resistance and Diabetes. Front Endocrinol (Lausanne). 2018 Aug 30;9:503. doi: 10.3389/fendo.2018.00503. PMID: 30214428; PMCID: PMC6125308.
URL	https://www.targetmol.com/recombinant-protein/hgf_protein_human_recombinant_hfc_

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