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- サプライヤー
- TargteMol
- カタログNo.
- TMPK-00305
- 製品名称
- TGFBR1 Protein, Human, Recombinant (mFc & Avi)
- タンパク質名
- TGFBR1
- Species
- Human
- HOST
- HEK293 Cells
- 100μg: -
- お問い合わせ
Overview
| Synonyms | tbetaR-I, TGFβRI, TGFbetaRI, LDS2A, TGF-β RI, TGFR-1, TGFB1R1, ACVRLK4, ALK-5, TGF-beta RI, tβR-I, LDS1A, AAT5, TGFBR1, TGF-bRI, SKR4 |
|---|---|
| Characteristics | Human TGFBR1, mFc Tag captured on CM5 Chip via Protein A can bind Human Mature TGF beta 1, No Tag with an affinity constant of 0.35 μM as determined in SPR assay. |
| Endotoxin Level | < 1 EU/μg by the LAL method. |
| Purity | > 95% |
| Description | transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR?98?5p. miR?98?5p overexpression resulted in the downregulation of TGFBR1 and the suppression of the viability, proliferation, migration and invasion of A549 and H1299 cells. TGFBR1 Protein, Human, Recombinant (mFc & Avi) is expressed in HEK293 mammalian cells with C-mFc-Avi tag. The predicted molecular weight is 38.2 kDa and the accession number is P36897-1. |
| Reference | Jiang F, et al. MicroRNA-98-5p inhibits proliferation and metastasis in non-small cell lung cancer by targeting TGFBR Int J Oncol. 2019 Jan;54(1):128-138. doi: 10.3892/ijo.2018.4610. Epub 2018 Oct 29. PMID: 30387848; PMCID: PMC6255066. |
| URL | https://www.targetmol.com/recombinant-protein/tgfbr1_protein_human_recombinant_mfc_avi_ |
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