NGF Protein, Mouse, Recombinant (E. colli) [TMPJ-01469]

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Synonyms	NGFB, β-NGF, NGF, Beta-Nerve Growth Factor, β-Nerve Growth Factor, Beta-NGF
Characteristics	Measured in a cell proliferation assay using TF?1 human erythroleukemic cells. The ED50 for this effect is 68.52 ng/mL.
Endotoxin Level	< 0.1 ng/?g (1 EU/?g) as determined by LAL test.
Purity	99%
Description	NGF is the first member discovered in the Neurotrophin family, which includes brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), and neurotrophin-4 (NT-4). These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. Mouse beta -NGF is a homodimer of two 120 amino acid polypeptides. It shares approximately 90% homology at the amino acid level with human beta -NGF and 95.8% with rat beta -NGF. NGF signaling has been shown to play an important role in neuroprotection and repair. β-NGF acts as a growth and differentiation factor for B lymphocytes, and enhances B-cell survival. It is a potent neurotrophic factor that signals through its receptor β-NGFR, and plays a crucial role in the development and preservation of the sensory and sympathetic nervous systems.
Reference	-
URL	https://www.targetmol.com/recombinant-protein/ngf_protein_human_recombinant_e_colli_

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