IL-2 Superkine Protein, Human, Recombinant (L100F, R101D, L105V, I106V, I112F) [TMPJ-01464]

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サプライヤー: TargteMol
カタログNo.: TMPJ-01464
製品名称: IL-2 Superkine Protein, Human, Recombinant (L100F, R101D, L105V, I106V, I112F)
タンパク質名: IL-2 Superkine
Species: Human
HOST: HEK293 Cells

Synonyms	TCGF, Aldesleukin, T-Cell Growth Factor, IL-2, Interleukin-2, IL2
Characteristics	1. Loaded Human IL-2RA-Fc on Protein A Biosensor, can bind Human IL-2 Superkine with an affinity constant of 10.4 nM as determined in BLI assay. (Regularly tested) 2. Measured in a cell proliferation assay using CTLL?2 mouse cytotoxic T cells. The ED50 for this effect is 151.39 pg/ml. (Regularly tested)
Endotoxin Level	< 0.1 ng/?g (1 EU/?g) as determined by LAL test.
Purity	SDS-PAGE: 100%; SEC-HPLC: 100%
Description	Interleukin-2(IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system，belongs to the IL-2 family. It is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages and oligodendrocytes. New research has shown that IL-2 mutant reduced toxicity while being more potent at stimulating anti-tumor effector immune cells.
Reference	-
URL	https://www.targetmol.com/recombinant-protein/il2_superkine_protein_human_recombinant_l100f_r101d_l105v_i106v_i112f_

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