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- サプライヤー
- TargteMol
- カタログNo.
- TMPJ-00990
- 製品名称
- S100B Protein, Mouse, Recombinant (His)
- タンパク質名
- S100B
- Species
- Mouse
- HOST
- E. coli
- 10μg: -
- お問い合わせ
Overview
| Synonyms | S-100 protein subunit beta, S-100 protein beta chain, S-100 protein subunit β, Protein S100-B, S100b, S100 beta, S-100 protein β chain, S100 β, S100 calcium binding protein B, S100 calcium-binding protein B |
|---|---|
| Characteristics | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Endotoxin Level | < 0.1 ng/?g (1 EU/?g) as determined by LAL test. |
| Purity | Greater than 95% as determined by reducing SDS-PAGE |
| Description | S100-B, is an acidic protein with a molecular weight of 21 kDa belonging to the S100 family. S100-B contains two EF-hand-type calcium-binding motifs separated by a hinge region with a hydrophobic cleft. S100-B plays an important role in neurodevelopment, differentiation, and brain construction. S100-B has neuroprotective effects, but at high concentrations S100-B is neurotoxic. Extracellular concentration of S100-B increases following brain damage, which easily penetrates into cerebrospinal fluid in brain damage and then into the blood. S100-B is expressed and produced by astrocytes in vertebrate brains and in the CNS, and the astrocytes are the major cells producing S100-B protein in gray matter, as well as oligodendrocytes are the predominant S100-B in protein producing cells in white matter. The major advantage of using S100-B is that elevations in serum or CSF levels provide a sensitive measure for determining CNS injury at the molecular level before gross changes develop, enabling timely delivery of crucial medical intervention before irreversible damage occurs. In addition, S100-B, which is also present in Mouse melanocytes, is a reliable marker for melanoma malignancy both in bioptic tissue and in serum. |
| Reference | - |
| URL | https://www.targetmol.com/recombinant-protein/s100b_protein_mouse_recombinant_his_ |
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