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- サプライヤー
- TargteMol
- カタログNo.
- TMPJ-00735
- 製品名称
- PDGF-BB Protein, Human, Recombinant
- タンパク質名
- PDGF-BB
- Species
- Human
- HOST
- E. coli
- 10μg: -
- お問い合わせ
Overview
| Synonyms | PDGF-BB, PDGFBB |
|---|---|
| Characteristics | Measured in a cell proliferation assay using BALB/c 3T3 cells. The ED50 for this effect is 5-20 ng/ml. (QC verified) |
| Endotoxin Level | < 0.02 ng/?g (0.2 EU/?g) as determined by LAL test. |
| Purity | SDS-PAGE: 98.3%; SEC-HPLC: >99.9% |
| Description | Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma.Binding of PDGFB to its receptor elicits a variety of cellular responses. In addition, PDGFB is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound. |
| Reference | - |
| URL | https://www.targetmol.com/recombinant-protein/pdgf_bb_protein_human_recombinant |
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