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バイオ製品Bio Products

タンパク質、抗体、アッセイキット

タンパク質カタログ

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サプライヤー
TargteMol
カタログNo.
TMPJ-00327
製品名称
M-CSF/CSF1 Protein, Human, Recombinant (His)
タンパク質名
M-CSF/CSF1
Species
Human
HOST
HEK293 Cells
10μg: -
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Overview

Synonyms M-CSF, CSF-1, MCSF, CSF1, Macrophage Colony-Stimulating Factor 1, Lanimostim
Characteristics Measured in a cell proliferation assay using M?NFS?60 mouse myelogenous leukemia lymphoblast cells. The ED50 for this effect is 4.16 ng/ml. (Regularly tested)
Endotoxin Level < 0.001 ng/?g (0.01 EU/?g) as determined by LAL test.
Purity > 99.9%
Description Macrophage Colony-Stimulating Factors (m-csf) are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and themonocytes-macrophages. CSF-1 promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. It also plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. CSF-1 is required for normal male and female fertility and promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. it also plays a role in lipoprotein clearance.
Reference -
URL https://www.targetmol.com/recombinant-protein/m_csf_protein_human_recombinant_his_

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