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- サプライヤー
- TargteMol
- カタログNo.
- TMPJ-00254
- 製品名称
- TGF beta 3 Protein, Human/Mouse/Rat, Recombinant
- タンパク質名
- TGF beta 3
- Species
- Human,Mouse,Rat
- HOST
- HEK293 Cells
- 10μg: -
- お問い合わせ
Overview
| Synonyms | Latency-associated peptide, TGF-beta-3, Transforming growth factor beta-3, TGFB3, TGF-β-3, LAP, Transforming growth factor β-3 |
|---|---|
| Characteristics | Measured by its ability to inhibit the IL-4-dependent proliferation of TF-1 mouse T?cells.?The ED50 for this effect is 10-80 pg/ml. (QC verified) |
| Endotoxin Level | < 0.001 ng/?g (0.01 EU/?g) as determined by LAL test. |
| Purity | > 99.9% |
| Description | Transforming growth factor beta 3(TGFB3) is a member of a TGF -β superfamily which is defined by theirstructural and functional similarities. TGFB3 is secreted as a complex with LAP. This latent form of TGFB3becomes active upon cleavage by plasmin, matrix metalloproteases, thrombospondin -1, and a subset ofintegrins. It binds with high affinity to TGF- β RII, a type II serine/threonine kinase receptor. TGFB3 is involved incell differentiation, embryogenesis and development.It is believed to regulate molecules involved in cellularadhesion and extracellular matrix (ECM) formation during the process of palate development. Without TGF-β3,mammals develop a deformity known as a cleft palate. |
| Reference | - |
| URL | https://www.targetmol.com/recombinant-protein/tgfb3_protein_human_mouse_rat_recombinant |
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