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- サプライヤー
- TargteMol
- カタログNo.
- TMPH-03038
- 製品名称
- Cobra venom factor Protein, Naja kaouthia, Recombinant (His & SUMO)
- タンパク質名
- Cobra venom factor
- Species
- Naja kaouthia
- HOST
- E. coli
- 20μg: -
- お問い合わせ
Overview
| Synonyms | Cobra venom factor, Complement C3 homolog, CVFk, CVF |
|---|---|
| Characteristics | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Endotoxin Level | - |
| Purity | 90% |
| Description | Complement-activating protein in cobra venom. It is a structural and functional analog of complement component C3b, the activated form of C3. It binds factor B (CFB), which is subsequently cleaved by factor D (CFD) to form the bimolecular complex CVF/Bb. CVF/Bb is a C3/C5 convertase that cleaves both complement components C3 and C5. Structurally, it resembles the C3b degradation product C3c, which is not able to form a C3/C5 convertase. Unlike C3b/Bb, CVF/Bb is a stable complex and completely resistant to the actions of complement regulatory factors H (CFH) and I (CFI). Therefore, CVF continuously activates complement resulting in the depletion of complement activity. |
| Reference | - |
| URL | https://www.targetmol.com/recombinant-protein/cobra_venom_factor_protein_naja_kaouthia_recombinant_his_sumo |
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