タンパク質、抗体、アッセイキット
タンパク質カタログ
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法規制によっては、定価として記載の価格に追加の費用が発生する場合や供給出来ない場合がございますので、あらかじめご了承ください。
- サプライヤー
- TargteMol
- カタログNo.
- TMPH-02226
- 製品名称
- TEAD3 Protein, Human, Recombinant (His & SUMO)
- タンパク質名
- TEAD3
- Species
- Human
- HOST
- E. coli
- 20μg: -
- お問い合わせ
Overview
Synonyms | DTEF-1, TEA domain family member 3, Transcriptional enhancer factor TEF-5, TEAD3 |
---|---|
Characteristics | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
Endotoxin Level | - |
Purity | 90% |
Description | Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds to multiple functional elements of the human chorionic somatomammotropin-B gene enhancer. |
Reference | - |
URL | https://www.targetmol.com/recombinant-protein/tead3_protein_human_recombinant_his_sumo |