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- サプライヤー
- TargteMol
- カタログNo.
- TMPH-02225
- 製品名称
- TEAD2 Protein, Human, Recombinant (His & Myc)
- タンパク質名
- TEAD2
- Species
- Human
- HOST
- E. coli
- 20μg: -
- お問い合わせ
Overview
| Synonyms | TEA domain family member 2, Transcriptional enhancer factor TEF-4, TEAD2 |
|---|---|
| Characteristics | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Endotoxin Level | - |
| Purity | 93% |
| Description | Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds to the SPH and GT-IIC 'enhansons' (5'-GTGGAATGT-3'). May be involved in the gene regulation of neural development. Binds to the M-CAT motif. |
| Reference | - |
| URL | https://www.targetmol.com/recombinant-protein/tead2_protein_human_recombinant_his_myc |
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