Biotinylated Cynomolgus / Rhesus macaque TIGIT Protein, His,Avitag? (MALS verified) [TIT-C82E3]

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サプライヤー: AcroBioSystems
カタログNo.: TIT-C82E3
製品名称: Biotinylated Cynomolgus / Rhesus macaque TIGIT Protein, His,Avitag? (MALS verified)
タンパク質名: TIGIT
Species: Cynomolgus / Rhesus macaque
HOST: HEK293

Synonyms	-
Characteristics	This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag?). The protein has a calculated MW of 31.0 kDa. The protein migrates as 33-43 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level	N/A
Purity	90%
Description	T-cell immunoreceptor with Ig and ITIM domains (TIGIT) is also known as V-set and immunoglobulin domain-containing protein 9 (VSIG9), V-set and transmembrane domain-containing protein 3 (VSTM3),which belongs to single-pass type I membrane protein containing an immunoglobulin variable domain, a transmembrane domain and an immunoreceptor tyrosine-based inhibitory motif (ITIM). TIGIT is expressed at low levels on peripheral memory and regulatory CD4+ T-cells and NK cells and is up-regulated following activation of these cells (at protein level). TIGIT binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells.
Reference	-
URL	https://www.acrobiosystems.com/products/protein/tigit-cynomolgus-rhesus-macaque-tit-c82e3

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