ナミキ商事株式会社 医薬品及び創薬化学品の専門商社

医薬品及び創薬化学品の専門商社

検索検索

バイオ製品Bio Products

リコンビナントタンパク質

ACROBiosystems社 プロダクトリスト:Recombinant Protein

サプライヤー
AcroBioSystems
カタログNo.
TIT-C5223
製品名称
Cynomolgus / Rhesus macaque TIGIT Protein, His Tag (HPLC verified)
タンパク質名
TIGIT
Species
Cynomolgus / Rhesus macaque
HOST
HEK293
1mg: 672000円
お問い合わせ
1mg: 711200円
お問い合わせ

Overview

Synonyms -
Characteristics This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 15.2 kDa. The protein migrates as 18-30 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level 1.0 EU per μg
Purity 90%
Description T-cell immunoreceptor with Ig and ITIM domains (TIGIT) is also known as V-set and immunoglobulin domain-containing protein 9 (VSIG9), V-set and transmembrane domain-containing protein 3 (VSTM3),which belongs to single-pass type I membrane protein containing an immunoglobulin variable domain, a transmembrane domain and an immunoreceptor tyrosine-based inhibitory motif (ITIM). TIGIT is expressed at low levels on peripheral memory and regulatory CD4+ T-cells and NK cells and is up-regulated following activation of these cells (at protein level). TIGIT binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells.
Reference -
URL https://www.acrobiosystems.com/P2151-Cynomolgus--Rhesus-macaque-TIGIT-Protein-His-Tag-%28HPLC-verified%29.html

お問い合わせリスト(-)

お問い合わせフォーム