タンパク質、抗体、アッセイキット
タンパク質カタログ
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- サプライヤー
- AcroBioSystems
- カタログNo.
- THN-H5217
- 製品名称
- Human Thrombopoietin / TPO Protein, Research Grade
- タンパク質名
- Thrombopoietin
- Species
- Human
- HOST
- HEK293
Overview
| Synonyms | - |
|---|---|
| Characteristics | This protein carries no "tag". The protein has a calculated MW of 35.5 kDa. The protein migrates as 75 kDa±5 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation. |
| Endotoxin Level | 0.01 EU per μg |
| Purity | 95% |
| Description | Thrombopoietin (TPO) is a 332 amino acid glycoprotein made primarily in the liver and act as the major physiological regulator of platelet production. TPO binds the TPO receptor, activates JAK and STAT pathways, thus stimulating megakaryocyte growth and platelet production. Additionally, further investigation uncovered that thrombopoietin is a critical cytokine promoting hematopoietic rebound after myeloablation and its transcripts are expressed by multiple cellular sources. |
| Reference | - |
| URL | N/A |

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