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バイオ製品Bio Products

タンパク質、抗体、アッセイキット

タンパク質カタログ

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サプライヤー
AcroBioSystems
カタログNo.
TG3-H52H5
製品名称
Human Latent TGF-beta 3 / Latent TGFB3 Protein, His Tag
タンパク質名
TGF-beta 3
Species
Human
HOST
HEK293
1mg: 1,132,300円
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50ug: 92,500円
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Overview

Synonyms -
Characteristics This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 46.8 kDa. The protein migrates as 12 kDa and 40-43 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level 1.0 EU per μg
Purity 90%
Description Transforming growth factor beta 3 ( TGFB3) is also known as TGF-β3, is a polypeptide member of the transforming growth factor beta superfamily of cytokines. It is a secreted protein that performs many cellular functions, including regulates embryogenesis and cell differentiation and is required in various processes such as secondary palate development. TGF-beta 3 is similar with TGF-beta 1 and ?-beta 2, act as cellular switches to regulate immune function, cell proliferation, and epithelial?-mesenchymal transition. TGF-beta-3 is released from LAP by integrins: integrin-binding results in distortion of the LAP chain and subsequent release of the active TGF-beta-3. Once activated following release of LAP, TGF-beta-3 acts by binding to TGF-beta receptors (TGFBR1 and TGFBR2), which transduce signal.
Reference -
URL https://www.acrobiosystems.com/products/protein/tgf-beta-3-human-tg3-h52h5

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