Human TGF-beta 3 / TGFB3 Protein, premium grade [TG3-H5213]

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Synonyms	-
Characteristics	This protein carries no "tag". The protein has a calculated MW of 12.7 kDa. The protein migrates as 12 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE).
Endotoxin Level	0.1 EU per μg
Purity	95%
Description	Transforming growth factor beta 3 ( TGFB3) is also known as TGF-β3, is a polypeptide member of the transforming growth factor beta superfamily of cytokines. It is a secreted protein that performs many cellular functions, including regulates embryogenesis and cell differentiation and is required in various processes such as secondary palate development. TGF-beta 3 is similar with TGF-beta 1 and ?-beta 2, act as cellular switches to regulate immune function, cell proliferation, and epithelial?-mesenchymal transition. TGF-beta-3 is released from LAP by integrins: integrin-binding results in distortion of the LAP chain and subsequent release of the active TGF-beta-3. Once activated following release of LAP, TGF-beta-3 acts by binding to TGF-beta receptors (TGFBR1 and TGFBR2), which transduce signal.
Reference	-
URL	https://www.acrobiosystems.com/products/protein/tgf-beta-3-human-tg3-h5213

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