Biotinylated Human Coagulation Factor III / Tissue Factor Protein, Fc,Avitag? (MALS & SPR verified) [TF3-H82F3]

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サプライヤー: AcroBioSystems
カタログNo.: TF3-H82F3
製品名称: Biotinylated Human Coagulation Factor III / Tissue Factor Protein, Fc,Avitag? (MALS & SPR verified)
タンパク質名: Coagulation Factor III
Species: Human
HOST: HEK293

Synonyms	-
Characteristics	This protein carries a human IgG1 Fc tag at the C-terminus, followed by an Avi tag (Avitag?). The protein has a calculated MW of 52.9 kDa. The protein migrates as 65-75 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level	1.0 EU per μg
Purity	90%
Description	Full-length tissue factor (TF) is a transmembrane receptor and cofactor for factor (F)VII/FVIIa. In addition to full-length TF, an alternative spliced (as) form of TF can be generated that lacks the transmembrane domain and is released fromcells. In contrast to TF, asTF has low procoagulant activity because it lacks the transmembrane domain. Tissue factor is expressed by cells around blood vessels, such as adventitial fibroblasts, and body surfaces, such as epithelial cells, and plays a critical role in hemostasis. TF also contributes to various forms of thrombosis. Many cancers, particularly adenocarcinomas, express high levels of TF. A high level of tumor TF expression is associated with poor prognosis in many types of cancers, including breast, prostate, colorectal, and pancreatic cancer.
Reference	-
URL	https://www.acrobiosystems.com/products/protein/coagulation-factor-iii-human-tf3-h82f3

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