Human Coagulation Factor III / Tissue Factor Protein, Fc Tag (active enzyme, MALS verified) [TF3-H5253]

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サプライヤー: AcroBioSystems
カタログNo.: TF3-H5253
製品名称: Human Coagulation Factor III / Tissue Factor Protein, Fc Tag (active enzyme, MALS verified)
タンパク質名: Coagulation Factor III
Species: Human
HOST: HEK293

Synonyms	-
Characteristics	This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 51.2 kDa. The protein migrates as 60-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level	1.0 EU per μg
Purity	95%
Description	Full-length tissue factor (TF) is a transmembrane receptor and cofactor for factor (F)VII/FVIIa. In addition to full-length TF, an alternative spliced (as) form of TF can be generated that lacks the transmembrane domain and is released fromcells. In contrast to TF, asTF has low procoagulant activity because it lacks the transmembrane domain. Tissue factor is expressed by cells around blood vessels, such as adventitial fibroblasts, and body surfaces, such as epithelial cells, and plays a critical role in hemostasis. TF also contributes to various forms of thrombosis. Many cancers, particularly adenocarcinomas, express high levels of TF. A high level of tumor TF expression is associated with poor prognosis in many types of cancers, including breast, prostate, colorectal, and pancreatic cancer.
Reference	-
URL	https://www.acrobiosystems.com/products/protein/coagulation-factor-iii-human-tf3-h5253

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