タンパク質、抗体、アッセイキット
タンパク質カタログ
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- サプライヤー
- AcroBioSystems
- カタログNo.
- TAU-H81E3
- 製品名称
- Biotinylated Human Tau-441 / 2N4R (1-441) Protein, His,Avitag? (MALS verified)
- タンパク質名
- Tau
- Species
- Human
- HOST
- E. coli
Overview
| Synonyms | - |
|---|---|
| Characteristics | This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag?). The protein has a calculated MW of 49.5 kDa. The protein migrates as 55-65 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE). |
| Endotoxin Level | N/A |
| Purity | 90% |
| Description | Tau 441 (2N4R) is the longest human brain tau isoform, containing two N-terminal inserts and four microtubule-binding repeats. It stabilizes neuronal microtubules, but its pathological hyperphosphorylation leads to paired helical filament aggregation. Tau 441 constitutes the core component of neurofibrillary tangles in Alzheimer's disease and related tauopathies. |
| Reference | 4467 |
| URL | https://www.acrobiosystems.com/products/protein/tau-human-tau-h81e3 |

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