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ACROBiosystems社 プロダクトリスト:Recombinant Protein

サプライヤー
AcroBioSystems
カタログNo.
TAI-H82F6
製品名称
Biotinylated Human TACI / TNFRSF13B Protein, Fc,Avitag?
タンパク質名
TACI
Species
Human
HOST
HEK293
25ug: 98000円
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200ug: 425600円
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Overview

Synonyms -
Characteristics This protein carries a human IgG1 Fc tag at the C-terminus, followed by an Avi tag (Avitag?). The protein has a calculated MW of 46.7 kDa. The protein migrates as 33-40 kDa and 47-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level 1.0 EU per μg
Purity 90%
Description Transmembrane activator and CAML interactor (TACI), also known as tumor necrosis factor receptor superfamily member 13B (TNFRSF13B). It was originally discovered because of its ability to interact with calcium-modulator and cyclophilin ligand (CAML). TACI was later found to play a crucial role in humoral immunity by interacting with two members of the TNF family: BAFF and APRIL.
The present study demonstrated that, in NSCLC, a proliferation-inducing ligand (APRIL), B-cell maturation antigen (BCMA)and transmembrane activator and CAML interactor (TACI) proteins are abnormally expressed by immunohistochemistry, reverse transcription-quantitative polymerase chain reaction and western blotting. In addition, the expression of APRIL, BCMA and TACI were observed to be involved in extracellular signal-regulated kinase (ERK)1/2 activation in A549 cells.
Reference -
URL https://www.acrobiosystems.com/P2550-Biotinylated-Human-TACI--TNFRSF13B-Protein-FcAvitag%E2%84%A2.html

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