タンパク質、抗体、アッセイキット
タンパク質カタログ
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- サプライヤー
- AcroBioSystems
- カタログNo.
- ST1-H5283
- 製品名称
- Human STEAP1 Full Length Protein,?Twin-Strep,His?Tag (Detergent) (SPR verified)
- タンパク質名
- STEAP1
- Species
- Human
- HOST
- HEK293
Overview
| Synonyms | - |
|---|---|
| Characteristics | This protein carries a twin strep tag at the N-terminus and a polyhistidine tag at the C-terminus. The protein has a calculated MW of 44.7 kDa. The protein migrates as 40-42 kDa and 80 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to Glycosylation. |
| Endotoxin Level | 1.0 EU per μg |
| Purity | 85% |
| Description | Six-transmembrane epithelial antigen of the prostate 1 (STEAP1) is an integral membrane protein that is highly up-regulated on the cell surface of several human cancers, making it a promising therapeutic target to manage these diseases. It shares sequence homology with three enzymes (STEAP2-STEAP4) that catalyze the NADPH-dependent reduction of iron(III). Taking into account its high specificity and overexpression in human cancers, STEAP1 is nowadays a promising candidate to be imposed as a therapeutic target. |
| Reference | - |
| URL | https://www.acrobiosystems.com/products/protein/steap1-human-st1-h5283 |

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