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タンパク質カタログ
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- サプライヤー
- AcroBioSystems
- カタログNo.
- SPN-S5228
- 製品名称
- SARS-CoV-2 Spike Trimer Protein, His Tag (LP.8.1/Omicron) (MALS verified)
- タンパク質名
- Spike protein
- Species
- SARS-CoV-2
- HOST
- HEK293
Overview
| Synonyms | - |
|---|---|
| Characteristics | This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 137.8 kDa. The protein migrates as 140-180 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation. |
| Endotoxin Level | 1.0 EU per μg |
| Purity | 90% |
| Description | SARS-CoV-2 Spike Trimer Protein, His Tag (LP.8.1/Omicron) (SPN-S5228) is expressed from human 293 cells (HEK293). It contains AA Val 16 - Pro 1213 (Accession # QHD43416.1 (T19I, R21T, LPP24-26Del, A27S, S50L, H69del, V70del, V127F, G142D, Y144del, F157S, R158G, N211del, L212I, V213G, L216F, H245N, A264D, I332V, G339H, K356T, S371F, S373P, S375F, T376A, R403K, D405N, R408S, K417N, N440K, V445H, G446S, N450D, L452W, L455S, N460K, S477N, T478K, N481K, V483del, E484K, F486P, Q498R, N501Y, Y505H, E554K, A570V, D614G, P621S, H655Y, N679K, P681R, N764K, D796Y, S939F, Q954H, N969K, P1143L, R683A, R685A, F817P, A892P, A899P, A942P, K986P, V987P, ins16MPLF, S31del, F186L, R190S, R346T, V445R, F456L, Q493E, K1086R, V1104L)). The recombinant protein is expressed from human 293 cells (HEK293) with T4 fibritin trimerization motif and a polyhistidine tag at the C-terminus. Proline substitutions (F817P, A892P, A899P, A942P, K986P, V987P) and alanine substitutions (R683A and R685A) are introduced to stabilize the trimeric prefusion state of SARS-CoV-2 S protein and abolish the furin cleavage site, respectively. |
| Reference | - |
| URL | https://www.acrobiosystems.com/products/protein/spike-protein-sars-cov-2-spn-s5228 |
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