Biotinylated SARS-CoV-2 Spike Trimer Protein (C136F, Y144del, R190S, D215G, LA242-243del, Y449H, E484K, N501Y, D614G, H655Y, N679K, T716I, T859N), His,Avitag? (MALS verified) [SPN-C82Eq]

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サプライヤー: AcroBioSystems
カタログNo.: SPN-C82Eq
製品名称: Biotinylated SARS-CoV-2 Spike Trimer Protein (C136F, Y144del, R190S, D215G, LA242-243del, Y449H, E484K, N501Y, D614G, H655Y, N679K, T716I, T859N), His,Avitag? (MALS verified)
タンパク質名: Spike protein
Species: SARS-CoV-2
HOST: HEK293

Synonyms	-
Characteristics	This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag?). The protein has a calculated MW of 139.5 kDa. The protein migrates as 180-220 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level	N/A
Purity	95%
Description	Biotinylated SARS-CoV-2 Spike Trimer, His,Avitag (SPN-C82Ek) is the ectodomain of SARS-CoV-2 spike protein which contains AA Val 16 - Pro 1213 (Accession # QHD43416.1). The mutations C136F, Y144del, R190S, D215G, LA242-243del, Y449H, E484K, N501Y, D614G, H655Y, N679K, T716I, T859N were identified in the SARS-CoV-2 variant C.1.2. The recombinant protein is expressed from human 293 cells (HEK293) with T4 fibritin trimerization motif and a polyhistidine tag at the C-terminus. Proline substitutions (F817P, A892P, A899P, A942P, K986P, V987P) and alanine substitutions (R683A and R685A) are introduced to stabilize the trimeric prefusion state of SARS-CoV-2 S protein and abolish the furin cleavage site, respectively.
Reference	-
URL	https://www.acrobiosystems.com/P4315-Biotinylated-SARS-CoV-2-Spike-Trimer-Protein-%28C136F-Y144del-R190S-D215G-LA242-243del-Y449H-E484K-N501Y-D614G-H655Y-N679K-T716I-T859N%29-HisAvitag%E2%84%A2-%28MALS-verified%29.html

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