Biotinylated SARS-CoV-2 Spike Trimer Protein (P26S, HV69-70del, V126A, Y144del, LLA241-243del, H245Y, S477N, E484K, D614G, P681H, T1027I, D1118H), His,Avitag? (MALS verified) [SPN-C82Ed]

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サプライヤー: AcroBioSystems
カタログNo.: SPN-C82Ed
製品名称: Biotinylated SARS-CoV-2 Spike Trimer Protein (P26S, HV69-70del, V126A, Y144del, LLA241-243del, H245Y, S477N, E484K, D614G, P681H, T1027I, D1118H), His,Avitag? (MALS verified)
タンパク質名: Spike protein
Species: SARS-CoV-2
HOST: HEK293

Synonyms	-
Characteristics	This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag?). The protein has a calculated MW of 139.1 kDa. The protein migrates as 160-200 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level	N/A
Purity	95%
Description	Biotinylated SARS-CoV-2 Spike Trimer, His,Avitag (SPN-C82Ed) is expressed from human 293 cells (HEK293). It contains AA Val 16 - Pro 1213 (Accession # QHD43416.1). The mutations (P26S, HV69-70del, V126A, Y144del, LLA241-243del, H245Y, S477N, E484K, D614G, P681H, T1027I, D1118H) were identified in the SARS-CoV-2 variant B.1.620, which was found to circulate in Europe and Central Africa. Proline substitutions (F817P, A892P, A899P, A942P, K986P, V987P) and alanine substitutions (R683A and R685A) are introduced to stabilize the trimeric prefusion state of SARS-CoV-2 S protein and abolish the furin cleavage site, respectively.
Reference	-
URL	https://www.acrobiosystems.com/P4072-Biotinylated-SARS-CoV-2-Spike-Trimer-Protein-%28P26S-HV69-70del-V126A-Y144del-LLA241-243del-H245Y-S477N-E484K-D614G-P681H-T1027I-D1118H%29-HisAvitag%E2%84%A2-%28MALS-verified%29.html

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