Biotinylated SARS-CoV-2 Spike Trimer Protein (T19R, G142D, EF156-157del, R158G, L452R, T478K, D614G, P681R, D950N), His,Avitag? (MALS verified) [SPN-C82Ec]

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サプライヤー: AcroBioSystems
カタログNo.: SPN-C82Ec
製品名称: Biotinylated SARS-CoV-2 Spike Trimer Protein (T19R, G142D, EF156-157del, R158G, L452R, T478K, D614G, P681R, D950N), His,Avitag? (MALS verified)
タンパク質名: Spike protein
Species: SARS-CoV-2
HOST: HEK293

Synonyms	-
Characteristics	This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag?). The protein has a calculated MW of 139.5 kDa. The protein migrates as 160-200 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level	N/A
Purity	95%
Description	Biotinylated SARS-CoV-2 Spike Trimer, His,Avitag (SPN-C82Ec) is expressed from human 293 cells (HEK293). It contains AA Val 16 - Pro 1213 (Accession # QHD43416.1). The mutations (T19R, G142D, EF156-157del, R158G, L452R, T478K, D614G, P681R, D950N) were identified in the SARS-CoV-2 Delta variant (Pango lineage: B.1.617.2; other names: 21A/S:478K). Proline substitutions (F817P, A892P, A899P, A942P, K986P, V987P) and alanine substitutions (R683A and R685A) are introduced to stabilize the trimeric prefusion state of SARS-CoV-2 S protein and abolish the furin cleavage site, respectively.
Reference	-
URL	https://www.acrobiosystems.com/P4063-Biotinylated-SARS-CoV-2-Spike-Trimer-Protein-%28T19R-G142D-EF156-157del-R158G-L452R-T478K-D614G-P681R-D950N%29-HisAvitag%E2%84%A2-%28MALS-verified%29.html

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