リコンビナントタンパク質
ACROBiosystems社 プロダクトリスト:Recombinant Protein
- サプライヤー
- AcroBioSystems
- カタログNo.
- SPN-C52Hd
- 製品名称
- SARS-CoV-2 S protein (F817P, A892P, A899P, A942P, K986P, V987P), His Tag (MALS verified)
- タンパク質名
- Spike protein
- Species
- SARS-CoV-2
- HOST
- HEK293
Overview
Synonyms | - |
---|---|
Characteristics | This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 138.2 kDa. The protein is cleaved at furin site and divided into S1 (16-685) and S2 (686-1213). The protein migrates as 75-85 kDa, 90-100 kDa and 150-160 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Endotoxin Level | 1.0 EU per μg |
Purity | 95% |
Description | It's been reported that SARS-CoV-2 can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. |
Reference | - |
URL | https://www.acrobiosystems.com/P3680-SARS-CoV-2-S-protein-%28F817P-A892P-A899P-A942P-K986P-V987P%29-His-Tag-%28MALS-verified%29.html |