SARS-CoV-2 Spike Trimer Protein, His Tag (BQ.1.1.10/Omicron) (MALS verified) [SPN-C524m]

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サプライヤー: AcroBioSystems
カタログNo.: SPN-C524m
製品名称: SARS-CoV-2 Spike Trimer Protein, His Tag (BQ.1.1.10/Omicron) (MALS verified)
タンパク質名: Spike protein
Species: SARS-CoV-2
HOST: HEK293

Synonyms	-
Characteristics	This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 137.5 kDa. The protein migrates as 160-190 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level	1.0 EU per μg
Purity	95%
Description	SARS-CoV-2 Spike Trimer, His Tag (BQ.1.1.10/Omicron) (SPN-C524m) is expressed from human 293 cells (HEK293). It contains AA Val 16 - Pro 1213 (Accession # QHD43416.1 (T19I, LPP24-26del, A27S, HV69-70del, G142D, Y144del, V213G, G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, K444T, L452R, N460K, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K, R683A, R685A, F817P, A892P, A899P, A942P, K986P, V987P)). The spike mutations are identified on the SARS-CoV-2 Omicron variant (Pango lineage: BQ.1.1.10). The recombinant protein is expressed from human 293 cells (HEK293) with T4 fibritin trimerization motif and a polyhistidine tag at the C-terminus. Proline substitutions (F817P, A892P, A899P, A942P, K986P, V987P) and alanine substitutions (R683A and R685A) are introduced to stabilize the trimeric prefusion state of SARS-CoV-2 S protein and abolish the furin cleavage site, respectively.
Reference	-
URL	https://www.acrobiosystems.com/P5747-SARS-CoV-2-Spike-Trimer-Protein-His-Tag-%28BQ1110Omicron%29-%28MALS-verified%29.html

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