Human SLC7A11&SLC3A2 Full Length Protein, Flag,His Tag (Detergent) [SLS-H52D3]

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Synonyms	-
Characteristics	The SLC7A11 protein carries a Flag tag at the N-terminus and a polyhistidine tag at the C-terminus. The SLC3A2 protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 59.4 kDa & 69.9 kDa.
Endotoxin Level	N/A
Purity	N/A
Description	Cysteine plays an essential role in cellular redox homoeostasis as a key constituent of the tripeptide glutathione (GSH). A rate limiting step in cellular GSH synthesis is the availability of cysteine. However, circulating cysteine exists in the blood as the oxidised di-peptide cystine, requiring specialised transport systems for its import into the cell. System xc- is a dedicated cystine transporter, importing cystine in exchange for intracellular glutamate. To counteract elevated levels of reactive oxygen species in cancerous cells system xc- is frequently upregulated, making it an attractive target for anticancer therapies.
Reference	-
URL	https://www.acrobiosystems.com/products/protein/slc7a11-slc3a2-human-human-sls-h52d3

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