Human Siglec-7 / CD328 Protein, Fc (L118A, G120A, E201A) Tag (MALS verified) [SI7-H5257]

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サプライヤー: AcroBioSystems
カタログNo.: SI7-H5257
製品名称: Human Siglec-7 / CD328 Protein, Fc (L118A, G120A, E201A) Tag (MALS verified)
タンパク質名: Siglec-7
Species: Human
HOST: HEK293

Synonyms	-
Characteristics	This protein carries a Fc (L118A, G120A, E201A) tag at the C-terminus. The protein has a calculated MW of 63.3 kDa. The protein migrates as 70-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. Mutations (L118A, G120A, E201A /EU number: L235A/G237A/E318A) in human immunoglobulin G1 (hIgG1) Fc strongly reduce binding of the Fc mutant to cell expressed FcγRs, resulting in an almost 4-fold reduction in ADCC compared to that of wild type human IgG1.
Endotoxin Level	0.01 EU per μg
Purity	95%
Description	Human Siglec-7, Fc (L118A, G120A, E201A) Tag (SI7-H5257) is expressed from human 293 cells (HEK293). It contains AA Gln 19 - Leu 353 (Accession # Q9Y286-1).
Reference	-
URL	https://www.acrobiosystems.com/P4890-Human-Siglec-7--CD328-Protein-Fc-%28L118A-G120A-E201A%29-Tag-%28MALS-verified%29.html

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