Influenza A virus (strain A/Victoria/3/1975 H3N2) Polymerase acidic Protein, His Tag [PON-V51H3]

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サプライヤー: AcroBioSystems
カタログNo.: PON-V51H3
製品名称: Influenza A virus (strain A/Victoria/3/1975 H3N2) Polymerase acidic Protein, His Tag
タンパク質名: Polymerase acidic protein
Species: Influenza A virus (strain A/Victoria/3/1975 H3N2)
HOST: E. coli

Synonyms	-
Characteristics	This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 26.5 kDa. The protein migrates as 28-30 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under non-reducing (NR) condition (SDS-PAGE).
Endotoxin Level	N/A
Purity	90%
Description	Plays an essential role in viral RNA transcription and replication by forming the heterotrimeric polymerase complex together with PB1 and PB2 subunits. The complex transcribes viral mRNAs by using a unique mechanism called cap-snatching. It consists in the hijacking and cleavage of host capped pre-mRNAs. These short capped RNAs are then used as primers for viral mRNAs. The PB2 subunit is responsible for the binding of the 5' cap of cellular pre-mRNAs which are subsequently cleaved after 10-13 nucleotides by the PA subunit that carries the endonuclease activity.
Reference	-
URL	https://www.acrobiosystems.com/products/protein/polymerase-acidic-protein-influenza-a-virus-strain-a-victoria-3-1975-h3n2-pon-v51h3

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